LIST OF ABBREVIATIONS
INTRODUCTION ……..4
Chapter 1.REVIEW OF LITERATURES.
1.1 Historical note………………………………………………………9
1.2. Epidemiology ………………………………………………11
1.3. Aetiology and pathophysiology……………………………………12
1.4. Neural nets………………………………………………………….18
1.5. Differential diagnosis…………………………………………….20
1.6. Management………………………………………………………27
Chapter 2. MATERIALS AND METHODS
2.1. Main clinical characteristics of materials …………………………32
2.2. Methods of clinical research ……………………………………..32
2.3. Neuroimaging examination ………………………………………34
2.4. Cognitive functions………………………………………………36
2.5. Ophthalmoscopy ( eye’s fundus examination)……………………36
2.6. Statistical handling of data……………………………………….36
CHAPTER III.THE RESULTS OF THEIR RESEARCH
3.1. Clinical and neurological characteristics……………………….…37
3.2. The main etiology and clinical manifestations of CSVD…………38
3.3. Comparative neuropsychological evaluation of
cognitive disorders………………………………………………………………44
3.4. Early significant of neuroimaging data……………………………47
3.5. Lipid profile………………………………………………………..49
3.6. Fundus examination and correlation with cholesterol and
cognitive impairment…………………………………………………………..50
3.7. Regular take drugs and development of cognitive impairment……52
3.8. Assessment of neuropsychological and experimental psychological results in the dynamics of treatment……………………………………………54
DISCUSSION……………………………………………………………………55
CONCLUSION………………………………………………………………..60
PRACTIC RECOMMENDATIONS………………………………………….61
APPENDIX……………………………………………………………………62
Reference………………………………………………………………………………………………65